THE CCN FAMILY OF GENES
October 20-23, 2004
Palais du Grand Large - Saint-Malo - France
Wednesday, October 20, 2004
Registration and Check-in
Welcome and Opening remarks
Buffet
Introduction:
B. Perbal (France)
Thursday 21, Friday 22 and Saturday 23, 2004
Main session topics
TRANSCRIPTION REGULATION
A. Leask (England) The control of CTGF expression in normal and
scleroderma fibroblast
M. Goppelt-Struebe (Germany) Regulation of CTGF expression in endothelial cells
B. Chaqour (USA) Functional Significance of Cyr61/CCN1 Expression in Smooth
Muscle Cells
Additional speakers to be announced
RECEPTORS AND SIGNALING
N. Wahab (England) CCN2 modes of action
S. Lam (USA) Activation of integrin-mediated signaling pathways by CCN
proteins: physiological consequences
D. Brigstock (USA) CCN2: interactions with cell surface heparan sulfate
proteoglycans and intergins on fibrogenic cell types
L. Lau (USA) Matricellular actions of CCN protein
E. Kuiper (Holland) CCN2 in the human eye
C. Naus (Canada) CCN3 and gap junctions
Additional speakers to be announced
DIFFERENTIATION AND DEVELOPMENT
K. Lyons (USA) Overlapping functions for Cyr61 and CTGF in chondrogenesis
S. Kubota (Japan) CCN2 gene regulation in chondrocytic differentiation
J. Castellot (USA) CCN5 Regulates Both Vascular and Non-Vascular Smooth
Muscle Cell Function
M. Takigawa (Japan) The role of CCN2 in skeletal repair and regeneration
L. Desnoyer (USA) Role of WISP-1 in embryonic development
Additional speakers to be announced
TUMORIGENESIS
R. Lupu (USA) CCN1 and its involvement in breast cancer progression and drug
resistance
S. Banerjee (USA) CCN5 gene in human breast cancer: estrogen and progesterone
inducible expression and regulation of tumor cell proliferation
L. Gilmour CCN3 is Down-Regulated in Chronic Myeloid Leukaemia
(Ireland)
K. Scotlandi (Italy) Role of CCN genes in human sarcomas
P. Koeffler (USA) CYR61:tumor suppressor gene or oncogene?
E. Winterhager (Germany) Interaction of CCN3 with Cx43: a possible mechanism for
negative growth regulation of cell growth in choriocarcinoma cells
B. Perbal (France) CCN3 isoforms in normal and tumor conditions
Additional speakers to be announced
FIBROTIC PATHOBIOLOGY
P. Trackman (USA) Activity and novel regulation of CTGF in human gingival
fibroblasts
B. Riser (USA) Targeting CCN2 in the Diagnosis and Treatment of
Progressive Renal Fibrosis
R. Goldschmeding (Holland) CTGF detection in human plasma and urine
samples in diabetes and renal diseases
D. Hinton (USA) The role of CTGF in the pathogenesis of retinal fibrotic and
angiogenic disease
Additional speakers to be announced